3-bromo-2-keto-butyric acid ethyl ester

3-bromo-2-keto-butyric acid ethyl ester - Names and Identifiers

Name	Ethyl 3-bromo-2-oxobutyrate
Synonyms	Ethyl 3-bromo-2-oxobutyrate Ethyl α-BroMoethylglyoxalate Ethyl 3-bromo-2-oxobutanoate Ethyl a-Bromoethylglyoxalate 3-Bromo-2-oxobutanoic acid ethyl ester 3-Bromo-2-oxo-butyric acid ethyl ester 3-bromo-2-keto-butyric acid ethyl ester Butanoic acid, 3-bromo-2-oxo-, ethyl ester
CAS	57332-84-0

3-bromo-2-keto-butyric acid ethyl ester - Physico-chemical Properties

Molecular Formula	C6H9BrO3
Molar Mass	209.04
Density	1.474
Boling Point	213℃
Flash Point	83℃
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-bromo-2-keto-butyric acid ethyl ester - Upstream Downstream Industry

Raw Materials

2-HYDROXY-N-BUTYRIC ACID ETHYL ESTER
Ethyl 3-oxobutanoate sodium salt
Ethyl acetate
Carbon tetrachloride
2-Oxobutyric acid

3-bromo-2-keto-butyric acid ethyl ester - Introduction

Ethyl 3-bromo-2-oxobutyrate is an organic compound with the formula C6H9BrO3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless liquid
-Boiling point: About 196 ° C
-Density: about 1.58g/cm³
-Melting point: About -43 ° C
-Solubility: Soluble in organic solvents such as alcohols and ethers, insoluble in water

Use:
- Ethyl 3-bromo-2-oxobutyrate is used as a synthetic intermediate in organic synthesis. It can be used to synthesize organic compounds such as drugs, chemicals and ligands.
-It can be used to synthesize ester compounds, such as ethyl oxobutyrate.

Method:
Ethyl 3-bromo-2-oxobutyrate can be prepared by the following steps:
1. Butanedione and hydrogen bromide react to generate 3-bromobutanedione.
2.3-bromobutanedione is reacted with Ethyl carbonate to generate Ethyl 3-bromo-2-oxobutyrate under the catalysis of alkali.

Safety Information:
Ethyl 3-bromo-2-oxobutyrate is an organic compound, and its use should follow the following safety measures:
-The substance is irritating to the skin and eyes. Appropriate protective gloves and goggles should be worn when using it.
-Avoid inhaling its vapor or dust, and operate in a well-ventilated place.
-Keep away from fire and oxidant during storage, and keep the container tightly closed.
-Read and understand chemical safety specifications carefully before use.

Last Update：2024-04-09 02:00:50